BMP10 anticorps (N-Term)

N° du produit ABIN2782813

Détail du produit anti-BMP10 anticorps

Antigène: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Chien, Cheval, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMP10 est non-conjugé

Application: Western Blotting (WB)

Séquence: KFATDRTSMP SANIIRSFKN EDLFSQPVSF NGIRKYPLLF NVSIPHHEEV

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Bmp10. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Rat

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 421 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur BMP10

Antigène: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Autre désignation: Bmp10 (BMP10 Produits)

Synonymes: anticorps BMP10, anticorps si:dkey-13n15.5, anticorps Bmp10, anticorps BMP9, anticorps BMP-10, anticorps bone morphogenetic protein 10, anticorps BMP10, anticorps bmp10, anticorps LOC662386, anticorps Bmp10

Sujet: Bmp10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Bmp10 acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Bmp10 inhibits endothelial cell migration and growth.
Alias Symbols: Bmp10
Protein Size: 421

Poids moléculaire: 48 kDa

ID gène: 500245

NCBI Accession: NM_001031824, NP_001026994

UniProt: Q4AEG6

Pathways: Hormone Activity, Regulation of Muscle Cell Differentiation