HSD17B12 anticorps (C-Term)

N° du produit ABIN2782872

Détail du produit anti-HSD17B12 anticorps

Antigène: HSD17B12 (Hydroxysteroid (17-Beta) Dehydrogenase 12 (HSD17B12))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Porc, Lapin, Boeuf (Vache), Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD17B12 est non-conjugé

Application: Western Blotting (WB)

Séquence: SAETFVKSAI KTVGLQTRTT GYVIHSLMGS INSIMPRWMY FKIIMGFSKS

Homologie: Cow: 79%, Dog: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 79%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Hsd17b12. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Hsd17b12

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 312 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HSD17B12

Antigène: HSD17B12 (Hydroxysteroid (17-Beta) Dehydrogenase 12 (HSD17B12))

Autre désignation: Hsd17b12 (HSD17B12 Produits)

Sujet: Hsd17b12 catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in females. Hsd17b12 also has 3-ketoacyl-CoA reductase activity, reducing both long chain 3-ketoacyl-CoAs and long chain fatty acyl-CoAs, suggesting a role in long fatty acid elongation.
Alias Symbols: 2610510O05Rik, AI172963, KIK-I, Kik1
Protein Interaction Partner: Eed, DSK2, VPS9, NUB1, UBQLN1, SQSTM1, RAD23B, PSMD4, NBR1,
Protein Size: 312

Poids moléculaire: 35 kDa

ID gène: 56348

NCBI Accession: NM_019657, NP_062631

UniProt: O70503

Pathways: Steroid Hormone Biosynthesis