CLN6 anticorps (C-Term)

N° du produit ABIN2782927

L’anticorps anti-CLN6 Polyclonal Lapin est utilisé pour la détection de CLN6 dans des échantillons de Humain, Souris, Rat, Chien, Cheval, Cobaye, Boeuf (Vache), Lapin, Mouton, Poisson zèbre (Danio rerio) et Porc. Il a été validé pour WB et IHC.

Aperçu rapide pour CLN6 anticorps (C-Term) (ABIN2782927)

Antigène: CLN6 (Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Cobaye, Boeuf (Vache), Lapin, Mouton, Poisson zèbre (Danio rerio), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLN6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-CLN6 anticorps

Épitope: C-Term

Fonction: CLN6 Antibody - C-terminal region

Séquence: RLFLDSNGLF LFSSFALTLL LVALWVAWLW NDPVLRKKYP GVIYVPEPWA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against CLN6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CLN6

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47372-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CLN6

Antigène: CLN6 (Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6))

Autre désignation: CLN6

Sujet:

Background Information: CLN6 is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely CLN6 involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.

Gene Name: Ceroid-lipofuscinosis, neuronal 6, late infantile, variant

Alternative Symbols: nclf, CLN4A, HsT18960

Protein Name: Ceroid-lipofuscinosis neuronal protein 6

Poids moléculaire: 36kDa

ID gène: 54982

NCBI Accession: NP_060352

UniProt: Q9NWW5

Pathways: Glycosaminoglycan Metabolic Process