Anoctamin 10 anticorps (C-Term)

N° du produit ABIN2782940

L’anticorps Lapin Polyclonal anti-Anoctamin 10 a été validé pour WB. Il convient pour détecter Anoctamin 10 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio). Il y a 4+ publications disponibles.

Aperçu rapide pour Anoctamin 10 anticorps (C-Term) (ABIN2782940)

Antigène: Anoctamin 10 (ANO10)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Anoctamin 10 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Anoctamin 10 anticorps

Épitope: C-Term

Séquence: LKADIDATLY EQVILEKEMG TYLGTFDDYL ELFLQFGYVS LFSCVYPLAA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against TMEM16K. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human TMEM16K

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 660 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Anoctamin 10 (ABIN2782940)

Wanitchakool, Ousingsawat, Sirianant, Cabrita, Faria, Schreiber, Kunzelmann: "Cellular defects by deletion of ANO10 are due to deregulated local calcium signaling." dans: Cellular signalling, Vol. 30, pp. 41-49, (2016) (PubMed).

Schreiber, Kunzelmann: "Expression of anoctamins in retinal pigment epithelium (RPE)." dans: Pflügers Archiv : European journal of physiology, Vol. 468, Issue 11-12, pp. 1921-1929, (2016) (PubMed).

Hammer, Wanitchakool, Sirianant, Papiol, Monnheimer, Faria, Ousingsawat, Schramek, Schmitt, Margos, Michel, Kraiczy, Pawlita, Schreiber, Schulz, Fingerle, Tumani, Ehrenreich, Kunzelmann: "A Coding Variant of ANO10, Affecting Volume Regulation of Macrophages, Is Associated with Borrelia Seropositivity." dans: Molecular medicine (Cambridge, Mass.), Vol. 21, pp. 26-37, (2015) (PubMed).

Tian, Schreiber, Kunzelmann: "Anoctamins are a family of Ca2+-activated Cl- channels." dans: Journal of cell science, Vol. 125, Issue Pt 21, pp. 4991-8, (2013) (PubMed).

Détails sur Anoctamin 10

Antigène: Anoctamin 10 (ANO10)

Autre désignation: TMEM16K

Sujet: TMEM16K is a multi-pass membrane protein. It belongs to the anoctamin family. TMEM16K may act as a calcium-activated chloride channel.
Alias Symbols: FLJ10375, MGC47890, SCAR10, TMEM16K
Protein Interaction Partner: UBC,
Protein Size: 660

Poids moléculaire: 76 kDa

ID gène: 55129

NCBI Accession: NM_018075, NP_060545

UniProt: Q9NW15