Anoctamin 10 anticorps (C-Term)

N° du produit ABIN2782940

Détail du produit anti-Anoctamin 10 anticorps

Antigène: Anoctamin 10 (ANO10)

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Poisson zèbre (Danio rerio), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Anoctamin 10 est non-conjugé

Application: Western Blotting (WB)

Séquence: LKADIDATLY EQVILEKEMG TYLGTFDDYL ELFLQFGYVS LFSCVYPLAA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against TMEM16K. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human TMEM16K

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 660 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Anoctamin 10 (ABIN2782940)

Wanitchakool, Ousingsawat, Sirianant, Cabrita, Faria, Schreiber, Kunzelmann: "Cellular defects by deletion of ANO10 are due to deregulated local calcium signaling." dans: Cellular signalling, Vol. 30, pp. 41-49, (2016) (PubMed).

Schreiber, Kunzelmann: "Expression of anoctamins in retinal pigment epithelium (RPE)." dans: Pflügers Archiv : European journal of physiology, Vol. 468, Issue 11-12, pp. 1921-1929, (2016) (PubMed).

Hammer, Wanitchakool, Sirianant, Papiol, Monnheimer, Faria, Ousingsawat, Schramek, Schmitt, Margos, Michel, Kraiczy, Pawlita, Schreiber, Schulz, Fingerle, Tumani, Ehrenreich, Kunzelmann: "A Coding Variant of ANO10, Affecting Volume Regulation of Macrophages, Is Associated with Borrelia Seropositivity." dans: Molecular medicine (Cambridge, Mass.), Vol. 21, pp. 26-37, (2015) (PubMed).

Tian, Schreiber, Kunzelmann: "Anoctamins are a family of Ca2+-activated Cl- channels." dans: Journal of cell science, Vol. 125, Issue Pt 21, pp. 4991-8, (2013) (PubMed).

Détails sur Anoctamin 10

Antigène: Anoctamin 10 (ANO10)

Autre désignation: TMEM16K (ANO10 Produits)

Synonymes: anticorps TMEM16K, anticorps ano10, anticorps zgc:114140, anticorps tmem16k, anticorps SCAR10, anticorps AI604832, anticorps Tmem16k, anticorps RGD1308260, anticorps anoctamin 10, anticorps anoctamin 10a, anticorps transmembrane protein 16K, anticorps anoctamin 10 L homeolog, anticorps ANO10, anticorps ano10, anticorps ano10a, anticorps MCYG_02694, anticorps MGYG_08424, anticorps ano10.L, anticorps Ano10

Sujet: TMEM16K is a multi-pass membrane protein. It belongs to the anoctamin family. TMEM16K may act as a calcium-activated chloride channel.
Alias Symbols: FLJ10375, MGC47890, SCAR10, TMEM16K
Protein Interaction Partner: UBC,
Protein Size: 660

Poids moléculaire: 76 kDa

ID gène: 55129

NCBI Accession: NM_018075, NP_060545

UniProt: Q9NW15