KIRREL anticorps (Middle Region)

N° du produit ABIN2782952

Cet anticorps Lapin Polyclonal détecte spécifiquement KIRREL dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval et Lapin.Il a été cité dans 1 publication.

Aperçu rapide pour KIRREL anticorps (Middle Region) (ABIN2782952)

Antigène: KIRREL (NEPH1) (Kin of IRRE Like 1 (NEPH1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIRREL est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KIRREL anticorps

Épitope: Middle Region

Fonction: KIRREL1 Antibody - middle region

Séquence: FLEVGTLERY TVERTNSGSG VLSTLTINNV MEADFQTHYN CTAWNSFGPG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against KIRREL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human KIRREL

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47408-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-KIRREL (ABIN2782952)

Ito, Sugihara, Asaka, Toyama, Yoshihara, Furuichi, Wada, Asano: "Glycoprotein hyposialylation gives rise to a nephrotic-like syndrome that is prevented by sialic acid administration in GNE V572L point-mutant mice." dans: PLoS ONE, Vol. 7, Issue 1, pp. e29873, (2012) (PubMed).

Détails sur KIRREL

Antigène: KIRREL (NEPH1) (Kin of IRRE Like 1 (NEPH1))

Autre désignation: KIRREL1

Sujet:

Background Information: NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2, MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).[supplied by OMIM, Mar 2008]

Gene Name: kirre like nephrin family adhesion molecule 1

Alternative Symbols: NEPH1, KIRREL, NPHS23

Protein Name: kin of IRRE-like protein 1

Poids moléculaire: 84 kDa

ID gène: 55243

NCBI Accession: NP_060710

UniProt: Q96J84

Pathways: Regulation of Actin Filament Polymerization