AGPAT5 anticorps (N-Term)

N° du produit ABIN2782960

Il existe 1 publication pour ce produit. L’anticorps anti-AGPAT5 Polyclonal Lapin est utilisé pour la détection de AGPAT5 dans des échantillons de Humain, Rat, Boeuf (Vache), Porc et Saccharomyces cerevisiae. Il a été validé pour WB.

Aperçu rapide pour AGPAT5 anticorps (N-Term) (ABIN2782960)

Antigène: AGPAT5 (1-Acylglycerol-3-Phosphate O-Acyltransferase 5 (Lysophosphatidic Acid Acyltransferase, Epsilon) (AGPAT5))

Reactivité: Humain, Rat, Boeuf (Vache), Porc, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AGPAT5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-AGPAT5 anticorps

Épitope: N-Term

Fonction: AGPAT5 Antibody - N-terminal region

Séquence: RLLSAFLPAR FYQALDDRLY CVYQSMVLFF FENYTGVQIL LYGDLPKNKE

Homologie: Cow: 86%, Human: 100%, Pig: 86%, Rat: 79%, Yeast: 77%

Attributs du produit: This is a rabbit polyclonal antibody against AGPAT5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human AGPAT5

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47429-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-AGPAT5 (ABIN2782960)

Agarwal, Barnes, Garg: "Functional characterization of human 1-acylglycerol-3-phosphate acyltransferase isoform 8: cloning, tissue distribution, gene structure, and enzymatic activity." dans: Archives of biochemistry and biophysics, Vol. 449, Issue 1-2, pp. 64-76, (2006) (PubMed).

Détails sur AGPAT5

Antigène: AGPAT5 (1-Acylglycerol-3-Phosphate O-Acyltransferase 5 (Lysophosphatidic Acid Acyltransferase, Epsilon) (AGPAT5))

Autre désignation: AGPAT5

Sujet:

Background Information: Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80 % homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis.

Gene Name: 1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)

Alternative Symbols: LPAATE, 1AGPAT5

Protein Name: 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

Poids moléculaire: 42kDa

ID gène: 55326

NCBI Accession: NP_060831

UniProt: Q9NUQ2