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ADCY10 anticorps (N-Term)

ADCY10 Reactivité: Humain, Rat, Souris, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2782970
  • Antigène Voir toutes ADCY10 Anticorps
    ADCY10 (Adenylate Cyclase 10 (Soluble) (ADCY10))
    Épitope
    • 15
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    N-Term
    Reactivité
    Humain, Rat, Souris, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval
    Hôte
    • 34
    Lapin
    Clonalité
    • 34
    Polyclonal
    Conjugué
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ADCY10 est non-conjugé
    Application
    • 19
    • 19
    • 13
    • 13
    • 12
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    VGHTVRHEYT VIGQKVNLAA RMMMYYPGIV TCDSVTYNGS NLPAYFFKEL
    Homologie
    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against SAC. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human SAC
    Top Product
    Discover our top product ADCY10 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 1610 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Corredor, Trakhtenberg, Pita-Thomas, Jin, Hu, Goldberg: "Soluble adenylyl cyclase activity is necessary for retinal ganglion cell survival and axon growth." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 22, pp. 7734-44, (2012) (PubMed).

  • Antigène
    ADCY10 (Adenylate Cyclase 10 (Soluble) (ADCY10))
    Autre désignation
    SAC (ADCY10 Produits)
    Synonymes
    anticorps HCA2, anticorps RP1-313L4.2, anticorps SAC, anticorps SACI, anticorps Sacy, anticorps Sac, anticorps 4930431D04Rik, anticorps 4931412F17, anticorps sAC, anticorps ADCY10, anticorps SACY, anticorps adenylate cyclase 10, anticorps adenylate cyclase 10 (soluble), anticorps ADCY10, anticorps Adcy10
    Sujet
    SAC belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction.The protein encoded by this gene belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: HCA2, RP1-313L4.2, SACI, SAC, Sacy
    Protein Interaction Partner: PTGIR, SSTR5,
    Protein Size: 1610
    Poids moléculaire
    187 kDa
    ID gène
    55811
    NCBI Accession
    NM_018417, NP_060887
    UniProt
    Q96PN6
    Pathways
    cAMP Metabolic Process
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