FTO anticorps (N-Term)

N° du produit ABIN2782980

Cet anticorps Lapin Polyclonal détecte spécifiquement FTO dans WB et IP. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Mouton, Porc, Lapin, Cheval et Saccharomyces cerevisiae.

Aperçu rapide pour FTO anticorps (N-Term) (ABIN2782980)

Antigène: FTO (Fat Mass and Obesity-Associated (FTO))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Mouton, Porc, Lapin, Cheval, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FTO est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-FTO anticorps

Épitope: N-Term

Fonction: Fto Antibody - N-terminal region

Séquence: MKRVQTAEER EREAKKLRLL EELEDTWLPY LTPKDDEFYQ QWQLKYPKLV

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Yeast: 90%

Attributs du produit: This is a rabbit polyclonal antibody against Fto. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Mouse

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47473-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur FTO

Antigène: FTO (Fat Mass and Obesity-Associated (FTO))

Autre désignation: Fto

Sujet:

Background Information: Fto is a dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Fto has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Fto has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Fto has no activity towards 1-methylguanine and no detectable activity towards double-stranded DNA. Fto requires molecular oxygen, alpha-ketoglutarate and iron. Fto contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Fto contributes to the regulation of body size and body fat accumulation.

Gene Name: Fat mass and obesity associated

Alternative Symbols: AW743446, mKIAA1752

Protein Name: Alpha-ketoglutarate-dependent dioxygenase FTO

Poids moléculaire: 58kDa

ID gène: 26383

NCBI Accession: NP_036066

UniProt: Q8BGW1