FTO anticorps (Middle Region)

N° du produit ABIN2782981

L’anticorps anti-FTO Polyclonal Lapin est utilisé pour la détection de FTO dans des échantillons de Humain, Souris, Rat, Chien, Lapin, Cheval et Cobaye. Il a été validé pour WB.

Aperçu rapide pour FTO anticorps (Middle Region) (ABIN2782981)

Antigène: FTO (Fat Mass and Obesity-Associated (FTO))

Reactivité: Humain, Souris, Rat, Chien, Lapin, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FTO est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FTO anticorps

Épitope: Middle Region

Fonction: FTO Antibody - middle region

Séquence: WWCQPMAQLE ALWKKMEGVT NAVLHEVKRE GLPVEQRNEI LTAILASLTA

Homologie: Dog: 86%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against FTO. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human FTO

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47474-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur FTO

Antigène: FTO (Fat Mass and Obesity-Associated (FTO))

Autre désignation: FTO

Sujet:

Background Information: The exact function of this gene is not know. Studies in mice suggest that it may be involved in nucleic acid demethylation, and that its mRNA level is regulated by feeding and fasting. Genomewide association studies of type 2 diabetes indicate this gene as a diabetes susceptibility locus. Mutation in this gene has been associated with growth retardation, developmental delay, coarse facies, and early death.

Gene Name: Fat mass and obesity associated

Alternative Symbols: GDFD, ALKBH9, BMIQ14

Protein Name: Alpha-ketoglutarate-dependent dioxygenase FTO

Poids moléculaire: 58kDa

ID gène: 79068

NCBI Accession: NP_001073901

UniProt: Q9C0B1