FTO anticorps (Middle Region)

N° du produit ABIN2782981

Détail du produit anti-FTO anticorps

Antigène: FTO (Fat Mass and Obesity-Associated (FTO))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Lapin, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FTO est non-conjugé

Application: Western Blotting (WB)

Séquence: WWCQPMAQLE ALWKKMEGVT NAVLHEVKRE GLPVEQRNEI LTAILASLTA

Homologie: Dog: 86%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against FTO. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human FTO

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 505 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FTO

Antigène: FTO (Fat Mass and Obesity-Associated (FTO))

Autre désignation: FTO (FTO Produits)

Synonymes: anticorps AW743446, anticorps mKIAA1752, anticorps RGD1305121, anticorps FTO, alpha-ketoglutarate dependent dioxygenase, anticorps fat mass and obesity associated, anticorps fat mass and obesity associated L homeolog, anticorps FTO, anticorps Fto, anticorps fto.L

Sujet: The exact function of this gene is not know. Studies in mice suggest that it may be involved in nucleic acid demethylation, and that its mRNA level is regulated by feeding and fasting. Genomewide association studies of type 2 diabetes indicate this gene as a diabetes susceptibility locus. Mutation in this gene has been associated with growth retardation, developmental delay, coarse facies, and early death.
Alias Symbols: KIAA1752, MGC5149
Protein Interaction Partner: UBC, SUMO1, NEDD8, BCCIP, CNDP2, DAK, NDRG1, NPEPPS, SLC9A3R1, CTSA, PEPD, MVD, LDHB, LDHA, EEF2, CKB,
Protein Size: 505

Poids moléculaire: 58 kDa

ID gène: 79068

NCBI Accession: NM_001080432, NP_001073901

UniProt: Q9C0B1