MGA (C-Term) anticorps

N° du produit ABIN2444597

L’anticorps anti-MGA Polyclonal Lapin est utilisé pour la détection de MGA dans des échantillons de Humain, Boeuf (Vache), Chien, Cheval, Souris, Porc, Lapin et Rat. Il a été validé pour WB.

Aperçu rapide pour MGA (C-Term) anticorps (ABIN2444597)

Antigène: MGA

Reactivité: Humain, Boeuf (Vache), Chien, Cheval, Souris, Porc, Lapin, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Détail du produit

Épitope: C-Term

Fonction: MGA Antibody - C-terminal region

Séquence: ASLQMKRESQ NPDQKDETNS IKREQETKKV LQSEGEAVDP EANVIKQNSG

Homologie: Cow: 92%, Dog: 85%, Horse: 92%, Human: 100%, Mouse: 79%, Pig: 92%, Rabbit: 79%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against MGA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MGA

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47556-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détail du antigène

Antigène: MGA

Sujet:

Background Information: MGA functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes and functions as a repressor or an activator. It binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. It suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. It function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor

Gene Name: MAX gene associated

Alternative Symbols: MAD5, MXD5

Protein Name: MAX gene-associated protein

Poids moléculaire: 76kDa

ID gène: 23269

UniProt: Q8IWI9