MAFK anticorps (N-Term)

N° du produit ABIN2783019

L’anticorps Lapin Polyclonal anti-MAFK a été validé pour WB. Il convient pour détecter MAFK dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio), Chien, Cheval, Lapin et Mouton.

Aperçu rapide pour MAFK anticorps (N-Term) (ABIN2783019)

Antigène: MAFK (Transcription Factor MafK (MAFK))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio), Chien, Cheval, Lapin, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAFK est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAFK anticorps

Épitope: N-Term

Séquence: KEAGENAPVL SDDELVSMSV RELNQHLRGL TKEEVTRLKQ RRRTLKNRGY

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 79%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against MAFK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MAFK

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 156 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MAFK

Antigène: MAFK (Transcription Factor MafK (MAFK))

Autre désignation: MAFK

Sujet: The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2. NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, PBGD and FECH. NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG, or MafK) and p45. Both subunits are members of the activator protein-1 superfamily of bZIP proteins. Maf homodimers suppress transcription at NFE2 sites.The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD, MIM 176000) and ferrochelatase (FECH, MIM 177000). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM].
Alias Symbols: FLJ32205, MGC71717, NFE2U, P18
Protein Interaction Partner: NFE2L2, SMAD3, PARP1, HIF1A, UBC, SUMO2, Bach1, HDAC3, HDAC2, HDAC1, CREBBP, RELA, KAT6A, TP53, BACH2, NFE2L3, NFE2, MARS, MAFK, NFE2L1, HOXD12,
Protein Size: 156

Poids moléculaire: 17 kDa

ID gène: 7975

NCBI Accession: NM_002360, NP_002351

UniProt: O60675