MORF4L1 anticorps (Middle Region)

N° du produit ABIN2783048

Détail du produit anti-MORF4L1 anticorps

Antigène: MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MORF4L1 est non-conjugé

Application: Western Blotting (WB)

Séquence: PEELKPWLVD DWDLITRQKQ LFYLPAKKNV DSILEDYANY KKSRGNTDNK

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 93%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against Morf4l1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Mouse

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 362 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MORF4L1

Antigène: MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))

Autre désignation: Morf4l1 (MORF4L1 Produits)

Synonymes: anticorps Eaf3, anticorps HsT17725, anticorps MEAF3, anticorps MORFRG15, anticorps MRG15, anticorps S863-6, anticorps TEG-189, anticorps Tex189, anticorps mKIAA4002, anticorps MORF4L2, anticorps CG6363, anticorps DmMRG15, anticorps Dmel\\CG6363, anticorps Dmrg15, anticorps Mrg15, anticorps dMRG15, anticorps dMrg15, anticorps l(3)j6A3, anticorps zgc:92289, anticorps mortality factor 4 like 1, anticorps MORF-related gene 15, anticorps MRG15, anticorps mortality factor 4 like 1 S homeolog, anticorps MORF4L1, anticorps Morf4l1, anticorps MRG15, anticorps CpipJ_CPIJ013367, anticorps morf4l1.S, anticorps morf4l1

Sujet: Morf4l1 is a component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
Alias Symbols: KIAA4002, MGC102415, MGC103105, MGC118047, MORFRG15, MRG15, TEG-189, Tex189, mKIAA4002
Protein Interaction Partner: Nanog, Hdac1, Phf12, Sin3b, Rb1, MRFAP1, Vezf1, Rnf2, Kdm5b, SIN3A, TLE1, PFN2,
Protein Size: 362

Poids moléculaire: 41 kDa

ID gène: 21761

NCBI Accession: NM_001039147, NP_001034236

UniProt: P60762

Pathways: Chromatin Binding