PSMC3IP anticorps (Middle Region)

N° du produit ABIN2783050

Détail du produit anti-PSMC3IP anticorps

Antigène: PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))

Épitope: Middle Region

Reactivité: Souris, Humain, Rat, Chien, Boeuf (Vache), Lapin, Cheval, Chévre, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMC3IP est non-conjugé

Application: Western Blotting (WB)

Séquence: RLKNIKAATN HVTPEEKEQV YRERQKYCKE WRKRKRMATE LSDAILEGYP

Homologie: Cow: 93%, Dog: 100%, Goat: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against PSMC3IP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PSMC3IP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 217 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PSMC3IP

Antigène: PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))

Autre désignation: PSMC3IP (PSMC3IP Produits)

Synonymes: anticorps PSMC3IP, anticorps Arabidopsis Hop2 homolog, anticorps T6J4.9, anticorps T6J4_9, anticorps C79099, anticorps GT198, anticorps HOP2, anticorps Tbpip, anticorps HUMGT198A, anticorps ODG3, anticorps TBPIP, anticorps Gt198, anticorps zgc:86785, anticorps PSMC3 interacting protein, anticorps homologous-pairing protein 2 homolog, anticorps Homologous-pairing protein 2 homolog, anticorps homologous-pairing protein 2 homolog-like, anticorps Tat-binding protein 1(Tbp-1)-interacting protein (TBPIP), anticorps proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein, anticorps PSMC3 interacting protein L homeolog, anticorps PSMC3IP, anticorps LOC726449, anticorps LOC100165513, anticorps hop2, anticorps psmc3ip, anticorps LOC100633854, anticorps LOC100650062, anticorps LOC789362, anticorps AHP2, anticorps Psmc3ip, anticorps psmc3ip.L

Sujet: PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.
Alias Symbols: GT198, HOP2, TBPIP, ODG3, HUMGT198A
Protein Interaction Partner: PSMC3, PSMC3IP, THRB, ESR2, AR, RXRA, NR3C1,
Protein Size: 217

Poids moléculaire: 25 kDa

ID gène: 29893

NCBI Accession: NM_016556, NP_057640

UniProt: Q9P2W1