ALDOA anticorps (N-Term)

N° du produit ABIN2783231

Cité dans 2 publications. Cet anticorps anti-ALDOA Polyclonal Lapin (ABIN2783231) détecte spécifiquement ALDOA dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Cobaye, Cheval, Poisson zèbre (Danio rerio) et Mouton.

Aperçu rapide pour ALDOA anticorps (N-Term) (ABIN2783231)

Antigène: ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))

Reactivité: Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Cobaye, Cheval, Poisson zèbre (Danio rerio), Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALDOA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ALDOA anticorps

Épitope: N-Term

Séquence: MPYQYPALTP EQKKELSDIA HRIVAPGKGI LAADESTGSI AKRLQSIGTE

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 93%, Sheep: 82%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against ALDOA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ALDOA

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 364 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ALDOA (ABIN2783231)

Braceland, McLoughlin, Tinsley, Wallace, Cockerill, McLaughlin, Eckersall: "Serum enolase: a non-destructive biomarker of white skeletal myopathy during pancreas disease (PD) in Atlantic salmon Salmo salar L." dans: Journal of fish diseases, Vol. 38, Issue 9, pp. 821-31, (2015) (PubMed).

Mao, Yang, Xu, Sang, Lu, Yang, Zhang, Zhong, Huang, Zhang: "[Significance of Golgi glycoprotein 73, a new tumor marker in diagnosis of hepatocellular carcinoma: a primary study]." dans: Zhonghua yi xue za zhi, Vol. 88, Issue 14, pp. 948-51, (2008) (PubMed).

Détails sur ALDOA

Antigène: ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))

Autre désignation: ALDOA

Sujet: ALDOA is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia.This gene product, Aldolase A (fructose-bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants which encode the same protein.
Alias Symbols: ALDA, MGC10942, MGC17716, MGC17767, GSD12
Protein Interaction Partner: HUWE1, UBC, IFNA4, FUS, ALDOC, ALDOA, SUMO2, SUMO3, MDM2, ADRB2, SUZ12, TNPO3, CS, RAD52, VCPKMT, PIAS4, GALNT6, IQCB1, VCAM1, MLH1, ITGA4, HSP90AB1, HSP90AA1, FN1, ATF2, BCAT2, ALDOB, LIG4, PGK1, LGALS1, HSPD1, AKT1, MYOC, CDK2, CUL2, CUL3, CUL4B, ISG15,
Protein Size: 364

Poids moléculaire: 39 kDa

ID gène: 226

NCBI Accession: NM_000034, NP_000025

UniProt: P04075

Pathways: Ribonucleoside Biosynthetic Process