UMPS anticorps (C-Term)

N° du produit ABIN2783243

Cité dans 1 publication. Cet anticorps anti-UMPS Polyclonal Lapin (ABIN2783243) détecte spécifiquement UMPS dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Lapin, Cobaye, Cheval, Chien, Boeuf (Vache), Porc et Saccharomyces cerevisiae.

Aperçu rapide pour UMPS anticorps (C-Term) (ABIN2783243)

Antigène: UMPS (Uridine Monophosphate Synthetase (UMPS))

Reactivité: Humain, Souris, Rat, Lapin, Cobaye, Cheval, Chien, Boeuf (Vache), Porc, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UMPS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-UMPS anticorps

Épitope: C-Term

Fonction: UMPS Antibody - C-terminal region

Séquence: VGFISGSRVS MKPEFLHLTP GVQLEAGGDN LGQQYNSPQE VIGKRGSDII

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%, Yeast: 75%

Attributs du produit: This is a rabbit polyclonal antibody against UMPS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human UMPS

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48147-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-UMPS (ABIN2783243)

Ishikawa, Kondo, Yamaguchi, Sakamoto, Fujisawa: "Effect of varicocelectomy on patients with unobstructive azoospermia and severe oligospermia." dans: BJU international, Vol. 101, Issue 2, pp. 216-8, (2008) (PubMed).

Détails sur UMPS

Antigène: UMPS (Uridine Monophosphate Synthetase (UMPS))

Autre désignation: UMPS

Sujet:

Background Information: OPRT (UMPS) is involved in early events of pancreatic and gallbladder carcinogenesis and invasion of hepatocellular carcinomas. Orotate phosphoribosyltransferase is involved in the invasion and metastasis of colorectal carcinoma. Determination of OPRT levels in gastric carcinoma tissue enables to predict the response to S-1-based neoadjuvant/adjuvant chemotherapy.

Gene Name: Uridine monophosphate synthetase

Alternative Symbols: OPRT

Protein Name: Uridine 5'-monophosphate synthase

Poids moléculaire: 52kDa

ID gène: 7372

NCBI Accession: NP_000364

UniProt: P11172

Pathways: Ribonucleoside Biosynthetic Process