Adenylate Kinase 1 anticorps (N-Term)

N° du produit ABIN2783244

Cet anticorps Lapin Polyclonal détecte spécifiquement Adenylate Kinase 1 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Cobaye, Mouton, Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour Adenylate Kinase 1 anticorps (N-Term) (ABIN2783244)

Antigène: Adenylate Kinase 1 (AK1)

Reactivité: Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Cobaye, Mouton, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Adenylate Kinase 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Adenylate Kinase 1 anticorps

Épitope: N-Term

Séquence: HLSTGDLLRS EVSSGSARGK KLSEIMEKGQ LVPLETVLDM LRDAMVAKVN

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Sheep: 92%, Zebrafish: 77%

Attributs du produit: This is a rabbit polyclonal antibody against AK1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human AK1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 194 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Adenylate Kinase 1

Antigène: Adenylate Kinase 1 (AK1)

Autre désignation: AK1

Sujet: Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: UBC, IDH1, APP, TERF2IP, TINF2, TERF1, TRIM63, FHL2, KMT2C,
Protein Size: 194

Poids moléculaire: 22 kDa

ID gène: 203

NCBI Accession: NM_000476, NP_000467

UniProt: P00568

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process