eEF1A1 anticorps (C-Term)

N° du produit ABIN2783254

Cet anticorps Lapin Polyclonal détecte spécifiquement eEF1A1 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Mouton, Lapin, Cheval, Cobaye et Chévre et a été mentionné dans 1 publication.

Aperçu rapide pour eEF1A1 anticorps (C-Term) (ABIN2783254)

Antigène: eEF1A1 (EEF1A1) (Eukaryotic Translation Elongation Factor 1 alpha 1 (EEF1A1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Mouton, Lapin, Cheval, Cobaye, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp eEF1A1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-eEF1A1 anticorps

Épitope: C-Term

Séquence: IVDMVPGKPM CVESFSDYPP LGRFAVRDMR QTVAVGVIKA VDKKAAGAGK

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against EEF1A1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human EEF1A1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 462 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-eEF1A1 (ABIN2783254)

Yan, Zhang, Chen, Gutmann, Xiong, Xiao, Huang: "Reduced T-cadherin expression and promoter methylation are associated with the development and progression of hepatocellular carcinoma." dans: International journal of oncology, Vol. 32, Issue 5, pp. 1057-63, (2008) (PubMed).

Détails sur eEF1A1

Antigène: eEF1A1 (EEF1A1) (Eukaryotic Translation Elongation Factor 1 alpha 1 (EEF1A1))

Autre désignation: EEF1A1

Sujet: EEF1A1 is an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66 % of patients with Felty syndrome.This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66 % of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CCS-3, CCS3, EEF-1, EEF1A, EF-Tu, EF1A, FLJ25721, GRAF-1EF, HNGC:16303, LENG7, MGC102687, MGC131894, MGC16224, PTI1, eEF1A-1, EE1A1
Protein Interaction Partner: GPX7, FUS, UBC, ISG15, SUMO3, CEP250, TUBGCP2, TUBG1, TP53, AURKA, SUMO2, STAU1, ALPL, LGR4, MDM2, RPA3, RPA2, RPA1, SHFM1, rev, PPP1CB, PFKP, GAPDH, PARK2, TRAP1, FBXO6, EGFR, ADRB2, RAD52, NPM1, CD81, BBS4, BBS2, BBS1, AICDA, STAT6, RBBP8, FN1, CDC25A,
Protein Size: 462

Poids moléculaire: 50 kDa

ID gène: 1915

NCBI Accession: NM_001402, NP_001393

UniProt: P68104