GBAS anticorps (Middle Region)
Aperçu rapide pour GBAS anticorps (Middle Region) (ABIN2783257)
Antigène
Voir toutes GBAS AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- VPRSGPNIYE LRSYQLRPGT MIEWGNYWAR AIRFRQDGNE AVGGFFSQIG
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 77%
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Attributs du produit
- This is a rabbit polyclonal antibody against GBAS. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human GBAS
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 286 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "The LIFEdb database in 2006." dans: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).
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: "The LIFEdb database in 2006." dans: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).
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- GBAS (Glioblastoma Amplified Sequence (GBAS))
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Autre désignation
- GBAS
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Sujet
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Chromosomal region 7p12, which contains GBAS, is amplified in approximately 40 % of glioblastomas, the most common and malignant form of central nervous system tumor.The predicted 286-amino acid protein contains a signal peptide, a transmembrane domain, and 2 tyrosine phosphorylation sites. The GBAS transcript is expressed most abundantly in heart and skeletal muscle. GBAS protein might be involved in vesicular transport.Chromosomal region 7p12, which contains GBAS, is amplified in approximately 40 % of glioblastomas, the most common and malignant form of central nervous system tumor.The predicted 286-amino acid protein contains a signal peptide, a transmembrane domain, and 2 tyrosine phosphorylation sites. The GBAS transcript is expressed most abundantly in heart and skeletal muscle. GBAS protein might be involved in vesicular transport.
Alias Symbols: NIPSNAP2
Protein Interaction Partner: VCP, UBC, SUMO1, NEDD8, AMOT, CDH1, CUL3, EBNA-LP, PRKCI, MAP1LC3A, MAP1LC3B, LARS, ANKFY1, GABARAPL1, GANAB, GABARAPL2, GABARAP, DDX39A, NAMPT, NPEPPS, LONP1, MTA2, SQSTM1, NIPSNAP1, WARS, TARS, PRKDC, PGK1, PFKP, PFAS, PA2G4, HK1, HADHA, FOXO3, FKBP4, A
Protein Size: 286 -
Poids moléculaire
- 34 kDa
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ID gène
- 2631
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NCBI Accession
- NM_001483, NP_001474
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UniProt
- O75323
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Pathways
- Ribonucleoside Biosynthetic Process
Antigène
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