CRYAB anticorps (C-Term)

N° du produit ABIN2783274

Détail du produit anti-CRYAB anticorps

Antigène: CRYAB (Crystallin, alpha B (CRYAB))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Mouton, Chien, Cobaye, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRYAB est non-conjugé

Application: Western Blotting (WB)

Séquence: KYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVT

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 92%

Attributs du produit: This is a rabbit polyclonal antibody against CRYAB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CRYAB

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 175 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CRYAB

Antigène: CRYAB (Crystallin, alpha B (CRYAB))

Autre désignation: CRYAB (CRYAB Produits)

Synonymes: anticorps CMD1II, anticorps CRYA2, anticorps CTPP2, anticorps CTRCT16, anticorps HSPB5, anticorps MFM2, anticorps Crya-2, anticorps Crya2, anticorps HspB5, anticorps AACRYA, anticorps CRYAB, anticorps cryab, anticorps cryab2, anticorps wu:fe37f08, anticorps zgc:91937, anticorps crystallin alpha B, anticorps crystallin, alpha B, anticorps hypothetical protein, anticorps crystallin, alpha B, a, anticorps crystallin, alpha B, b, anticorps CRYAB, anticorps Cryab, anticorps ZK1128.7, anticorps cryaba, anticorps cryabb

Sujet: Alpha crystallins are composed of: alpha-A and alpha-B, for acidic and basic, respectively. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases, a missense mutation cosegregated in a family with a desmin-related myopathy.
Alias Symbols: CRYA2, CTPP2, HSPB5
Protein Interaction Partner: CRYAB, CRYAA, KRTAP19-5, KRTAP8-1, TRAPPC6A, MRPL11, TNPO2, ACOT7, HSPB1, CASP7, CASP3, CASP2, PIDD1, DDX20, CRADD, B2M, APOC2, XIAP, CASP12, SOD1, HSPB2, HBA1, CASP9, CASP8, CASP6, ASB5, SMAD4, TRIM33, UBC, CCL22, CTNNB1, CRYGD, CDH1, SNCA, GFAP, FGF2, F
Protein Size: 175

Poids moléculaire: 20 kDa

ID gène: 1410

NCBI Accession: NM_001885

UniProt: P02511