TPM2 anticorps (C-Term)

N° du produit ABIN2783288

Cet anticorps anti-TPM2 est un anticorps Lapin Polyclonal détectant TPM2 dans WB et IHC. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio), Cobaye, Cheval, Porc et Mouton. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour TPM2 anticorps (C-Term) (ABIN2783288)

Antigène: TPM2 (Tropomyosin-2 (TPM2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio), Cobaye, Cheval, Porc, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TPM2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-TPM2 anticorps

Épitope: C-Term

Séquence: AETRAEFAER SVAKLEKTID DLEDEVYAQK MKYKAISEEL DNALNDITSL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 100%, Pig: 85%, Rabbit: 100%, Rat: 100%, Sheep: 85%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against TPM2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human TPM2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 284 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TPM2 (ABIN2783288)

Abdul-Hussein, Rahl, Moslemi, Tajsharghi: "Phenotypes of myopathy-related beta-tropomyosin mutants in human and mouse tissue cultures." dans: PLoS ONE, Vol. 8, Issue 9, pp. e72396, (2013) (PubMed).

Tajsharghi, Ohlsson, Lindberg, Oldfors: "Congenital myopathy with nemaline rods and cap structures caused by a mutation in the beta-tropomyosin gene (TPM2)." dans: Archives of neurology, Vol. 64, Issue 9, pp. 1334-8, (2007) (PubMed).

Détails sur TPM2

Antigène: TPM2 (Tropomyosin-2 (TPM2))

Autre désignation: TPM2

Sujet: TPM2 is beta-tropomyosin, an isoform of tropomyosin that is mainly expressed in slow, type 1 muscle fibers.The TPM2 gene encodes beta-tropomyosin, an isoform of tropomyosin that is mainly expressed in slow, type 1 muscle fibers (Tajsharghi et al., 2007 [PubMed 17846275]). See also TPM1 (MIM 191010), TPM3 (MIM 191030), and TPM4 (MIM 600317).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AMCD1, DA1, TMSB, DA2B, NEM4
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, HECTD1, SKIL, STAM, TPM4, TPM3, TPM1, SULT1A1, NONO, STMN1, DYNC1H1, DDX3X, DDB1, SRXN1, CPSF7, CORO1B, DSTN, SF3B2, AHCYL1, DDX46, TAF15, LRRK2, AKT1, SP1, ACTA1, S100A4, TPM2, PDLIM7, PIK3CG, RRAD, S100A2, JUN, ADRBK1, ACTB,
Protein Size: 284

Poids moléculaire: 33 kDa

ID gène: 7169

NCBI Accession: NM_003289, NP_003280

UniProt: P07951