TCAP anticorps (Middle Region)

N° du produit ABIN2783291

Cet anticorps Lapin Polyclonal détecte spécifiquement TCAP dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Chévre et Lapin.

Aperçu rapide pour TCAP anticorps (Middle Region) (ABIN2783291)

Antigène: TCAP (Titin-Cap (Telethonin) (TCAP))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Chévre, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCAP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TCAP anticorps

Épitope: Middle Region

Séquence: IQLQELLALE TALGGQCVDR QEVAEITKQL PPVVPVSKPG ALRRSLSRSM

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TCAP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TCAP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 167 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TCAP

Antigène: TCAP (Titin-Cap (Telethonin) (TCAP))

Autre désignation: TCAP

Sujet: Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in TCAP gene are associated with limb-girdle muscular dystrophy type 2G.Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMD1N, LGMD2G, T-cap, TELE, telethonin
Protein Interaction Partner: TRIM63, TRIM55, RELA, FYN, FAS, ATXN1, MDM2, TTN, PDPK1, MYOZ3, ANKRD2, MYOZ1, MSTN, MYOZ2,
Protein Size: 167

Poids moléculaire: 19 kDa

ID gène: 8557

NCBI Accession: NM_003673, NP_003664

UniProt: O15273