MDH1 anticorps (Middle Region)

N° du produit ABIN2783317

Cet anticorps Lapin Polyclonal détecte spécifiquement MDH1 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Lapin, Cheval, Cobaye, Poisson zèbre (Danio rerio), Chien et Chévre. Il a été cité dans 2+ publications.

Aperçu rapide pour MDH1 anticorps (Middle Region) (ABIN2783317)

Antigène: MDH1 (Malate Dehydrogenase 1, NAD (Soluble) (MDH1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Cheval, Cobaye, Poisson zèbre (Danio rerio), Chien, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MDH1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MDH1 anticorps

Épitope: Middle Region

Fonction: MDH1 Antibody - middle region

Séquence: NFSCLTRLDH NRAKAQIALK LGVTANDVKN VIIWGNHSST QYPDVNHAKV

Homologie: Cow: 100%, Dog: 93%, Goat: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against MDH1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MDH1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104805

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-MDH1 (ABIN2783317)

Nussbaumer, Asara, Teplytska, Murphy, Logan, Turck, Filiou: "Selective Mitochondrial Targeting Exerts Anxiolytic Effects In Vivo." dans: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 41, Issue 7, pp. 1751-8, (2016) (PubMed).

Povlsen, Løfgren, Dalgas, Birkler, Johannsen, Støttrup, Bøtker: "Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation." dans: PLoS ONE, Vol. 8, Issue 5, pp. e64093, (2013) (PubMed).

Détails sur MDH1

Antigène: MDH1 (Malate Dehydrogenase 1, NAD (Soluble) (MDH1))

Autre désignation: MDH1

Sujet:

Background Information: Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. MDH1 is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria.Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Malate dehydrogenase 1, NAD (soluble)

Alternative Symbols: KAR, MDHA, MOR2, DEE88, MDH-s, EIEE88, HEL-S-32, MGC:1375

Protein Name: Malate dehydrogenase, cytoplasmic

Poids moléculaire: 36kDa

ID gène: 4190

NCBI Accession: NP_005908

UniProt: P40925