MDH1 anticorps (Middle Region)

N° du produit ABIN2783317

Détail du produit anti-MDH1 anticorps

Antigène: MDH1 (Malate Dehydrogenase 1, NAD (Soluble) (MDH1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Cobaye, Chien, Poisson zèbre (Danio rerio), Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MDH1 est non-conjugé

Application: Western Blotting (WB)

Séquence: NFSCLTRLDH NRAKAQIALK LGVTANDVKN VIIWGNHSST QYPDVNHAKV

Homologie: Cow: 100%, Dog: 93%, Goat: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against MDH1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MDH1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 334 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-MDH1 (ABIN2783317)

Nussbaumer, Asara, Teplytska, Murphy, Logan, Turck, Filiou: "Selective Mitochondrial Targeting Exerts Anxiolytic Effects In Vivo." dans: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 41, Issue 7, pp. 1751-8, (2016) (PubMed).

Povlsen, Løfgren, Dalgas, Birkler, Johannsen, Støttrup, Bøtker: "Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation." dans: PLoS ONE, Vol. 8, Issue 5, pp. e64093, (2013) (PubMed).

Détails sur MDH1

Antigène: MDH1 (Malate Dehydrogenase 1, NAD (Soluble) (MDH1))

Autre désignation: MDH1 (MDH1 Produits)

Synonymes: anticorps MDH-s, anticorps MDHA, anticorps MGC:1375, anticorps MOR2, anticorps ODS1, anticorps B230377B03Rik, anticorps D17921, anticorps Mor-2, anticorps Mor2, anticorps MDL1, anticorps Mdhl, anticorps MDH, anticorps mdh-s, anticorps mdha, anticorps mor2, anticorps MDH-1, anticorps Mdh, anticorps Mdh-1, anticorps Mdh2, anticorps MdhD, anticorps cMdh, anticorps sMdh, anticorps malate dehydrogenase 1, anticorps malic enzyme 2, anticorps malate dehydrogenase 1, NAD (soluble), anticorps malate dehydrogenase 1 S homeolog, anticorps malate dehydrogenase, cytoplasmic, anticorps Malate dehydrogenase 1, anticorps MDH1, anticorps ME2, anticorps Mdh1, anticorps mdh1.S, anticorps LOC100280767

Sujet: Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. MDH1 is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria.Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MDH-s, MDHA, MGC:1375, MOR2
Protein Interaction Partner: ISG15, UBC, NEDD8, PARK2, HSP90AB1, HSP90AA1, FUS, IQCB1, SDHA, PGM1, LDHA, ESD, Htt, PRDX5, PRDX6, SLC9A3R1, AKT1, TERF2IP, TERF1, TP53, EGFR, MPP3, MDH1, GPD1,
Protein Size: 334

Poids moléculaire: 36 kDa

ID gène: 4190

NCBI Accession: NM_005917, NP_005908

UniProt: P40925