MTAP anticorps (N-Term)
Aperçu rapide pour MTAP anticorps (N-Term) (ABIN2783427)
Antigène
Voir toutes MTAP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- MTAP Antibody - N-terminal region
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Séquence
- ASGTTTTAVK IGIIGGTGLD DPEILEGRTE KYVDTPFGKP SDALILGKIK
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against MTAP. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human MTAP
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48574-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- MTAP (Methylthioadenosine phosphorylase (MTAP))
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Autre désignation
- MTAP
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Sujet
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Background Information: This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.
Gene Name: methylthioadenosine phosphorylase
Alternative Symbols: BDMF, MSAP, DMSFH, LGMBF, DMSMFH, c86fus, HEL-249
Protein Name: S-methyl-5'-thioadenosine phosphorylase
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Poids moléculaire
- 38kDa
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ID gène
- 4507
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UniProt
- Q13126
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Pathways
- Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
Antigène
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