PYGB anticorps (N-Term)

N° du produit ABIN2783431

L’anticorps anti-PYGB Polyclonal Lapin est utilisé pour la détection de PYGB dans des échantillons de Humain, Souris, Rat, Lapin, Mouton, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien, Cobaye et Cheval. Il a été validé pour WB et IHC.

Aperçu rapide pour PYGB anticorps (N-Term) (ABIN2783431)

Antigène: PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))

Reactivité: Humain, Souris, Rat, Lapin, Mouton, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PYGB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PYGB anticorps

Épitope: N-Term

Fonction: PYGB Antibody - N-terminal region

Séquence: QQHYYERDPK RIYYLSLEFY MGRTLQNTMV NLGLQNACDE AIYQLGLDLE

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against PYGB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PYGB

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48586-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PYGB

Antigène: PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))

Autre désignation: PYGB

Sujet:

Background Information: PYGB is a glycogen phosphorylase found predominantly in the brain. It forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Phosphorylase, glycogen, brain

Alternative Symbols: GPBB

Protein Name: Glycogen phosphorylase, brain form

Poids moléculaire: 97 kDa

ID gène: 5834

NCBI Accession: NP_002853

UniProt: P11216

Pathways: Cellular Glucan Metabolic Process