GMP Synthase anticorps (Middle Region)

N° du produit ABIN2783438

L’anticorps Lapin Polyclonal anti-GMP Synthase a été validé pour WB. Il convient pour détecter GMP Synthase dans des échantillons de Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Cheval, Lapin, Boeuf (Vache), Cobaye et Porc.

Aperçu rapide pour GMP Synthase anticorps (Middle Region) (ABIN2783438)

Antigène: GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Cheval, Lapin, Boeuf (Vache), Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GMP Synthase est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GMP Synthase anticorps

Épitope: Middle Region

Séquence: VCTALLNRAL NQEQVIAVHI DNGFMRKRES QSVEEALKKL GIQVKVINAA

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against GMPS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human GMPS

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 693 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GMP Synthase

Antigène: GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))

Autre désignation: GMPS

Sujet: In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.
Alias Symbols: -
Protein Interaction Partner: UBC, SUMO2, SUMO3, TNRC6B, SUMO1, NEDD8, COASY, EFHD2, PPME1, TSTA3, RCN1, RAB1A, PSMD5, PNP, MTAP, ENO2, FBXO6, AGPAT2, VCAM1, ITGA4, FN1, APRT, AHCY, CUL3, SIRT7, SUMO4, USP7, DDA1, PRKAG2, BABAM1, TCEAL1,
Protein Size: 693

Poids moléculaire: 77 kDa

ID gène: 8833

NCBI Accession: NM_003875, NP_003866

UniProt: P49915

Pathways: Ribonucleoside Biosynthetic Process