PAPSS2 anticorps (C-Term)

N° du produit ABIN2783448

Cité dans 1 publication. Cet anticorps anti-PAPSS2 Polyclonal Lapin (ABIN2783448) détecte spécifiquement PAPSS2 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour PAPSS2 anticorps (C-Term) (ABIN2783448)

Antigène: PAPSS2 (3'-phosphoadenosine 5'-phosphosulfate Synthase 2 (PAPSS2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAPSS2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PAPSS2 anticorps

Épitope: C-Term

Fonction: PAPSS2 Antibody - C-terminal region

Séquence: PARHNEFDFI SGTRMRKLAR EGENPPDGFM APKAWKVLTD YYRSLEKN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against PAPSS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human PAPSS2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48642-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PAPSS2 (ABIN2783448)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Détails sur PAPSS2

Antigène: PAPSS2 (3'-phosphoadenosine 5'-phosphosulfate Synthase 2 (PAPSS2))

Autre désignation: PAPSS2

Sujet:

Background Information: Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. PAPSS2 is one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene.Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Gene Name: 3'-phosphoadenosine 5'-phosphosulfate synthase 2

Alternative Symbols: SK2, BCYM4, ATPSK2

Protein Name: Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2

Poids moléculaire: 70kDa

ID gène: 9060

NCBI Accession: NP_001015880

UniProt: O95340

Pathways: Glycosaminoglycan Metabolic Process, Ribonucleoside Biosynthetic Process