CDY1 anticorps (C-Term)

N° du produit ABIN2783449

Détail du produit anti-CDY1 anticorps

Antigène: CDY1 (Chromodomain Protein, Y-Linked, 1 (CDY1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDY1 est non-conjugé

Application: Western Blotting (WB)

Séquence: FPRTWWQSAE DVHREKIQLD LEAEFYFTHL IVMFKSPRPA AMVLDRSQDF

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 85%, Human: 100%, Mouse: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against CDY1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CDY1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 554 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CDY1 (ABIN2783449)

Stouffs, Tournaye, Van der Elst, Haentjens, Liebaers, Lissens: "Do we need to search for gr/gr deletions in infertile men in a clinical setting?" dans: Human reproduction (Oxford, England), Vol. 23, Issue 5, pp. 1193-9, (2008) (PubMed).

Détails sur CDY1

Antigène: CDY1 (Chromodomain Protein, Y-Linked, 1 (CDY1))

Autre désignation: CDY1 (CDY1 Produits)

Synonymes: anticorps CDY, anticorps CDY1A, anticorps chromodomain Y-linked 1, anticorps CDY1

Sujet: CDY1 containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein.This gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. The human chromosome Y has two identical copies of this gene within a palindromic region, this record represents the more telomeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. Two protein isoforms are encoded by transcript variants of this gene. Additional transcript variants have been described, but their full-length nature has not been determined.
Alias Symbols: CDY, CDY1A
Protein Size: 554

Poids moléculaire: 62 kDa

ID gène: 9085

NCBI Accession: NM_004680, NP_004671

UniProt: A8K8F3