SULT1E1 anticorps (Middle Region)
Aperçu rapide pour SULT1E1 anticorps (Middle Region) (ABIN2783458)
Antigène
Voir toutes SULT1E1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- LMVAGHPNPG SFPEFVEKFM QGQVPYGSWY KHVKSWWEKG KSPRVLFLFY
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Homologie
- Dog: 85%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 83%, Rabbit: 92%, Rat: 83%
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Attributs du produit
- This is a rabbit polyclonal antibody against SULT1E1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human SULT1E1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 294 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Bisphenol A sulfonation is impaired in metabolic and liver disease." dans: Toxicology and applied pharmacology, Vol. 292, pp. 75-84, (2016) (PubMed).
: "Downregulation of sulfotransferase expression and activity in diseased human livers." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 41, Issue 9, pp. 1642-50, (2013) (PubMed).
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: "Bisphenol A sulfonation is impaired in metabolic and liver disease." dans: Toxicology and applied pharmacology, Vol. 292, pp. 75-84, (2016) (PubMed).
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- SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))
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Autre désignation
- SULT1E1
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Sujet
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Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors.
Alias Symbols: EST, EST-1, MGC34459, STE, ST1E1
Protein Interaction Partner: PDE9A, LRIF1, COPS6, RBM48, IGSF21, ENOX1, SETDB1, C14orf1, SULT2B1, UNC119, BMPR2, TP53, EEF1A1,
Protein Size: 294 -
Poids moléculaire
- 35 kDa
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ID gène
- 6783
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NCBI Accession
- NM_005420, NP_005411
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UniProt
- P49888
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Pathways
- Steroid Hormone Biosynthesis
Antigène
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