BHMT2 anticorps (Middle Region)
Aperçu rapide pour BHMT2 anticorps (Middle Region) (ABIN2783509)
Antigène
Voir toutes BHMT2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- GFVDLPEYPF GLESRVATRW DIQKYAREAY NLGVRYIGGC CGFEPYHIRA
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Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Rat: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against BHMT2. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human BHMT2
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 363 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- BHMT2 (Betaine--Homocysteine S-Methyltransferase 2 (BHMT2))
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Autre désignation
- BHMT2
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Sujet
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Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ20001
Protein Interaction Partner: APP,
Protein Size: 363 -
Poids moléculaire
- 40 kDa
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ID gène
- 23743
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NCBI Accession
- NM_017614, NP_060084
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UniProt
- Q9H2M3
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Pathways
- Methionine Biosynthetic Process
Antigène
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