NMNAT1 anticorps (N-Term)

N° du produit ABIN2783549

Cet anticorps Lapin Polyclonal détecte spécifiquement NMNAT1 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Cobaye, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Chévre, Cheval et Lapin.

Aperçu rapide pour NMNAT1 anticorps (N-Term) (ABIN2783549)

Antigène: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Reactivité: Humain, Souris, Rat, Cobaye, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Chévre, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NMNAT1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NMNAT1 anticorps

Épitope: N-Term

Fonction: NMNAT1 Antibody - N-terminal region

Séquence: PVGDAYKKKG LIPAYHRVIM AELATKNSKW VEVDTWESLQ KEWKETLKVL

Homologie: Cow: 93%, Dog: 93%, Goat: 79%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against NMNAT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human NMNAT1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48889-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur NMNAT1

Antigène: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Autre désignation: NMNAT1

Sujet:

Background Information: The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD (Zhang et al., 2003 [PubMed 12574164]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Nicotinamide nucleotide adenylyltransferase 1

Alternative Symbols: LCA9, NMNAT, PNAT1, SHILCA

Protein Name: Nicotinamide mononucleotide adenylyltransferase 1

Poids moléculaire: 32kDa

ID gène: 64802

NCBI Accession: NP_073624

UniProt: Q9HAN9