NEK11 anticorps (Middle Region)

N° du produit ABIN2783561

L’anticorps anti-NEK11 Polyclonal Lapin est utilisé pour la détection de NEK11 dans des échantillons de Humain, Rat, Boeuf (Vache) et Cheval. Il a été validé pour WB.

Aperçu rapide pour NEK11 anticorps (Middle Region) (ABIN2783561)

Antigène: NEK11 (NIMA (Never In Mitosis Gene A)-Related Kinase 11 (NEK11))

Reactivité: Humain, Rat, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NEK11 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NEK11 anticorps

Épitope: Middle Region

Fonction: NEK11 Antibody - middle region

Séquence: KEIRNEGSQP AYRTNQQDSD IEALARCLEN VLGCTSLDTK TITTMAEDMS

Homologie: Cow: 77%, Horse: 100%, Human: 100%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against NEK11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human NEK11

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48920-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur NEK11

Antigène: NEK11 (NIMA (Never In Mitosis Gene A)-Related Kinase 11 (NEK11))

Autre désignation: NEK11

Sujet:

Background Information: NEK11 is a member of the never in mitosis gene A family of kinases. NEK11 localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. It appears to play roles in DNA replication and response to genotoxic stress. NEK11 belongs to the NIMA family of kinases, which are involved in DNA replication and genotoxic stress responses (Noguchi et al., 2002 [PubMed 12154088]).[supplied by OMIM]. Sequence Note: removed 2 bases from the 3' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2937 AB071996.1 1-2937

Gene Name: NIMA (never in mitosis gene a)- related kinase 11

Alternative Symbols: FLJ23495

Protein Name: Serine/threonine-protein kinase Nek11

Poids moléculaire: 74kDa

ID gène: 79858

NCBI Accession: NP_079076

UniProt: Q8NG66