TTC5 anticorps (C-Term)
Aperçu rapide pour TTC5 anticorps (C-Term) (ABIN2783601)
Antigène
Voir toutes TTC5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- TTC5 Antibody - C-terminal region
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Séquence
- GDSVAIPEPN LRLHRIQHKG KDYSFSSVRV ETPLLLVVNG KPQGSSSQAV
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Homologie
- Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 86%, Rat: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against TTC5. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human TTC5
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8113735
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))
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Autre désignation
- TTC5
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Sujet
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Background Information: TTC5 is an adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. It is required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. It prevents p53/TP53 degradation by MDM2.
Gene Name: Tetratricopeptide repeat domain 5
Alternative Symbols: Strap, NEDCAFD
Protein Name: Tetratricopeptide repeat protein 5
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Poids moléculaire
- 49kDa
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ID gène
- 91875
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NCBI Accession
- NP_612385
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UniProt
- Q8N0Z6
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Pathways
- Chromatin Binding
Antigène
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