CDYL anticorps (N-Term)
Aperçu rapide pour CDYL anticorps (N-Term) (ABIN2783639)
Antigène
Voir toutes CDYL AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- YIHDFNRRHT EKQKESTLTR TNRTSPNNAR KQISRSTNSN FSKTSPKALV
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against CDYL. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the n terminal region of human CDYL
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 544 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells." dans: FEBS letters, Vol. 584, Issue 14, pp. 3198-202, (2010) (PubMed).
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: "A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells." dans: FEBS letters, Vol. 584, Issue 14, pp. 3198-202, (2010) (PubMed).
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- CDYL (Chromodomain Protein, Y-Like (CDYL))
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Autre désignation
- CDYL
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Sujet
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CDYL acts as repressor of transcription. CDYL has histone acetyltransferase activity, with a preference for histone H4.Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene.
Alias Symbols: CDYL1, DKFZP586C1622, MGC131936
Protein Interaction Partner: UBC, HECW2, HDAC2, HDAC1, MIER1, MIER2, EHMT2, RBBP4, MYC, SUZ12, EZH2, CTBP1, WIZ, ZNF644, SETDB1, SMARCB1, SMARCA4, REST, HIST1H3A, HTRA1,
Protein Size: 544 -
Poids moléculaire
- 60 kDa
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ID gène
- 9425
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NCBI Accession
- NM_004824, NP_004815
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UniProt
- Q9Y232
Antigène
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