B3GALTL anticorps (Middle Region)

N° du produit ABIN2783666

Détail du produit anti-B3GALTL anticorps

Antigène: B3GALTL (beta 1,3-Galactosyltransferase-Like (B3GALTL))

Épitope: Middle Region

Reactivité: Humain, Souris, Chien, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp B3GALTL est non-conjugé

Application: Western Blotting (WB)

Séquence: DYPKDYLSHQ VPISFHKHWN IDPVKVYFTW LAPSDEDKAR QETQKGFREE

Homologie: Dog: 93%, Human: 100%, Mouse: 79%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against B3GALTL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human B3GALTL

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 498 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur B3GALTL

Antigène: B3GALTL (beta 1,3-Galactosyltransferase-Like (B3GALTL))

Autre désignation: B3GALTL (B3GALTL Produits)

Synonymes: anticorps B3GLCT, anticorps B3GTL, anticorps B3Glc-T, anticorps Gal-T, anticorps beta3Glc-T, anticorps Gm1057, anticorps beta 3-glucosyltransferase, anticorps beta 3-glucosyltransferase L homeolog, anticorps beta-3-glucosyltransferase, anticorps B3GLCT, anticorps b3glct, anticorps b3glct.L, anticorps B3glct

Sujet: B3GALTL is the O-fucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. B3GALTL specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan.B3GALTL is a beta-1,3-glucosyltransferase involved in the synthesis of the unusual O-linked disaccharide glucosyl-beta-1,3-fucose-O- found on the thrombospondin (see THBS1, MIM 188060) type-1 repeats (TSRs) of many biologically important proteins. Biosynthesis of glucosyl-beta-1,3-fucose-O- is initiated by protein O-fucosyltransferase-2 (POFUT2, MIM 610249), which attaches the fucosyl residue to a serine or threonine within the TSR. B3GALTL subsequently transfers the glucose onto TSR-fucose (Hess et al., 2008 [PubMed 18199743]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-270 DN999521.1 41-310 271-457 AB101481.1 161-347 458-467 DN999521.1 499-508 468-1217 AB101481.1 358-1107 1218-1279 DA290408.1 515-576 1280-1607 AB101481.1 1170-1497 1608-2495 AY190526.1 1498-2385 2496-3459 AY190526.1 2387-3350 3460-4071 AV728071.1 87-698 4072-4221 AA769548.1 1-150 c
Alias Symbols: B3GTL, B3Glc-T, Gal-T, beta3Glc-T, B3GLCT
Protein Interaction Partner: UBC, ELAVL1,
Protein Size: 498

Poids moléculaire: 56 kDa

ID gène: 145173

NCBI Accession: NM_194318, NP_919299

UniProt: Q6Y288