PCDHGB1 anticorps (N-Term)

N° du produit ABIN2783725

Cet anticorps Lapin Polyclonal détecte spécifiquement PCDHGB1 dans WB. Il présente une réactivité envers Humain, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Souris, Rat et Poisson zèbre (Danio rerio).

Aperçu rapide pour PCDHGB1 anticorps (N-Term) (ABIN2783725)

Antigène: PCDHGB1 (Protocadherin gamma Subfamily B, 1 (PCDHGB1))

Reactivité: Humain, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Souris, Rat, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHGB1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PCDHGB1 anticorps

Épitope: N-Term

Séquence: SPDGSKYPVL LLEKPLDREH QSSHRLILTA MDGGDPPLSG TTHIWIRVTD

Homologie: Cow: 85%, Dog: 92%, Guinea Pig: 90%, Horse: 83%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%

Attributs du produit: This is a rabbit polyclonal antibody against PCDHGB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PCDHGB1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 810 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PCDHGB1

Antigène: PCDHGB1 (Protocadherin gamma Subfamily B, 1 (PCDHGB1))

Autre désignation: PCDHGB1

Sujet: PCDHGB1 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHGB1 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Alias Symbols: MGC119466, MGC119467, MGC119469, PCDH-GAMMA-B1
Protein Size: 810

Poids moléculaire: 85 kDa

ID gène: 56104

NCBI Accession: NM_032095, NP_115266

UniProt: Q3SY75