PCDHB13 anticorps (Middle Region)

N° du produit ABIN503033

Détail du produit anti-PCDHB13 anticorps

Antigène: PCDHB13 (Protocadherin beta 13 (PCDHB13))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHB13 est non-conjugé

Application: Western Blotting (WB)

Séquence: GKTFKINPLT GEIELKKQLD FEKLQSYEVN IEARDAGTFS GKCTVLIQVI

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PCDHB13. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PCDHB13

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 798 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PCDHB13

Antigène: PCDHB13 (Protocadherin beta 13 (PCDHB13))

Autre désignation: PCDHB13 (PCDHB13 Produits)

Synonymes: anticorps PCDH-BETA13, anticorps Pcdh3, anticorps Pcdbh6, anticorps PcdhbM, anticorps PCDHB13, anticorps protocadherin beta 13, anticorps protocadherin beta 12, anticorps protocadherin beta-8, anticorps PCDHB13, anticorps Pcdhb12, anticorps Pcdhb13, anticorps LOC518612

Sujet: PCDHB13 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
Alias Symbols: PCDH-BETA13
Protein Size: 798

Poids moléculaire: 85 kDa

ID gène: 56123

NCBI Accession: NM_018933, NP_061756

UniProt: Q9Y5F0