PCDHB14 anticorps (Middle Region)

N° du produit ABIN2783731

Détail du produit anti-PCDHB14 anticorps

Antigène: PCDHB14 (Protocadherin beta 14 (PCDHB14))

Épitope: Middle Region

Reactivité: Humain, Boeuf (Vache), Chien, Cheval, Souris, Porc, Lapin, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHB14 est non-conjugé

Application: Western Blotting (WB)

Séquence: YGKISYTFFH ASEDIRKTFE INPISGEVNL RSPLDFEVIQ SYTINIQATD

Homologie: Cow: 86%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PCDHB14. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PCDHB14

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PCDHB14

Antigène: PCDHB14 (Protocadherin beta 14 (PCDHB14))

Autre désignation: PCDHB14 (PCDHB14 Produits)

Sujet: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
Alias Symbols: PCDH-BETA14
Protein Size: 645

Poids moléculaire: 70 kDa

ID gène: 56122

NCBI Accession: NM_018934, NP_061757

UniProt: B4DPE2