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TMCO1 anticorps (C-Term)

L’anticorps Lapin Polyclonal anti-TMCO1 a été validé pour WB. Il convient pour détecter TMCO1 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio). Il y a 2+ publications disponibles.
N° du produit ABIN2783742

Aperçu rapide pour TMCO1 anticorps (C-Term) (ABIN2783742)

Antigène

Voir toutes TMCO1 Anticorps
TMCO1 (Transmembrane and Coiled-Coil Domains 1 (TMCO1))

Reactivité

  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte

  • 6
Lapin

Clonalité

  • 6
Polyclonal

Conjugué

  • 3
  • 1
  • 1
  • 1
Cet anticorp TMCO1 est non-conjugé

Application

  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 4
    • 2
    C-Term

    Séquence

    CSFIFLYILC TMSIRQNIQK ILGLAPSRAA TKQAGGFLGP PPPSGKFS

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

    Attributs du produit

    This is a rabbit polyclonal antibody against TMCO1. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the C terminal region of human TMCO1
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 188 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Sharma, Burdon, Chidlow, Klebe, Crawford, Dimasi, Dave, Martin, Javadiyan, Wood, Casson, Danoy, Griggs, Hewitt, Landers, Mitchell, Mackey, Craig: "Association of genetic variants in the TMCO1 gene with clinical parameters related to glaucoma and characterization of the protein in the eye." dans: Investigative ophthalmology & visual science, Vol. 53, Issue 8, pp. 4917-25, (2012) (PubMed).

    Burdon, Macgregor, Hewitt, Sharma, Chidlow, Mills, Danoy, Casson, Viswanathan, Liu, Landers, Henders, Wood, Souzeau, Crawford, Leo, Wang, Rochtchina, Nyholt, Martin, Montgomery, Mitchell, Brown et al.: "Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1. ..." dans: Nature genetics, Vol. 43, Issue 6, pp. 574-8, (2011) (PubMed).

  • Antigène

    TMCO1 (Transmembrane and Coiled-Coil Domains 1 (TMCO1))

    Autre désignation

    TMCO1

    Sujet

    TMCO1 belongs to the TMCO1 family. The exact function of TMCO1 remains unknown.
    Alias Symbols: HP10122, PCIA3, PNAS-136, RP11-466F5.7, TMCC4
    Protein Interaction Partner: UBC, FBXO6, SERINC1, LAMTOR3, SRSF5, RPS10, ABCC1, ELAVL1, UNC93B1,
    Protein Size: 188

    Poids moléculaire

    21 kDa

    ID gène

    54499

    NCBI Accession

    NM_019026, NP_061899

    UniProt

    Q9UM00
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