XYLT2 anticorps (C-Term)

N° du produit ABIN2783858

Détail du produit anti-XYLT2 anticorps

Antigène: XYLT2 (Xylosyltransferase II (XYLT2))

Épitope: C-Term

Reactivité: Souris, Humain, Rat, Chien, Lapin, Cheval, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XYLT2 est non-conjugé

Application: Western Blotting (WB)

Séquence: LRPGPWTVRL LQFWEPLGET RFLVLPLTFN RKLPLRKDDA SWLHAGPPHN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against XYLT2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human XYLT2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 865 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur XYLT2

Antigène: XYLT2 (Xylosyltransferase II (XYLT2))

Autre désignation: XYLT2 (XYLT2 Produits)

Synonymes: anticorps MGC89331, anticorps PXYLT2, anticorps XT-II, anticorps XT2, anticorps xylT-II, anticorps xt-II, anticorps E030002B02Rik, anticorps xylt-II, anticorps xylosyltransferase II, anticorps xylosyltransferase 2, anticorps xylt2, anticorps XYLT2, anticorps Xylt2

Sujet: XYLT2 is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis.The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: XT-II, XT2, xylT-II, PXYLT2
Protein Size: 865

Poids moléculaire: 97 kDa

ID gène: 64132

NCBI Accession: NM_022167, NP_071450

UniProt: Q9H1B5

Pathways: Glycosaminoglycan Metabolic Process