XYLT2 anticorps (C-Term)

N° du produit ABIN2783858

Cet anticorps anti-XYLT2 Polyclonal Lapin (ABIN2783858) détecte spécifiquement XYLT2 dans WB. L’anticorps est réactif avec des échantillons de Souris, Humain, Chien, Rat, Cheval, Lapin, Boeuf (Vache) et Cobaye.

Aperçu rapide pour XYLT2 anticorps (C-Term) (ABIN2783858)

Antigène: XYLT2 (Xylosyltransferase II (XYLT2))

Reactivité: Souris, Humain, Chien, Rat, Cheval, Lapin, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XYLT2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-XYLT2 anticorps

Épitope: C-Term

Fonction: XYLT2 Antibody - C-terminal region

Séquence: LRPGPWTVRL LQFWEPLGET RFLVLPLTFN RKLPLRKDDA SWLHAGPPHN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against XYLT2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human XYLT2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49703-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur XYLT2

Antigène: XYLT2 (Xylosyltransferase II (XYLT2))

Autre désignation: XYLT2

Sujet:

Background Information: XYLT2 is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis.The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Xylosyltransferase II

Alternative Symbols: SOS, XT2, XT-II, PXYLT2, xylT-II

Protein Name: Xylosyltransferase 2

Poids moléculaire: 97 kDa

ID gène: 64132

NCBI Accession: NP_071450

UniProt: Q9H1B5

Pathways: Glycosaminoglycan Metabolic Process