NDST4 anticorps (N-Term)
Aperçu rapide pour NDST4 anticorps (N-Term) (ABIN2783875)
Antigène
Voir toutes NDST4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- NDST4 Antibody - N-terminal region
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Séquence
- EDWTIFQYNH STYQPVLLTE LQTEKSLSSL SSKTLFATVI QDLGLHDGIQ
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 90%
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Attributs du produit
- This is a rabbit polyclonal antibody against NDST4. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human NDST4
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49737-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- NDST4 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 4 (NDST4))
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Autre désignation
- NDST4
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Sujet
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Background Information: NDST4 is an essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. It modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. NDST4 has low deacetylase activity but high sulfotransferase activity.
Gene Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
Alternative Symbols: N-HSST, NDST-4, NHSST4, N-HSST 4
Protein Name: Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4
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Poids moléculaire
- 101kDa
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ID gène
- 64579
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NCBI Accession
- NP_072091
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UniProt
- Q9H3R1
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Pathways
- Glycosaminoglycan Metabolic Process
Antigène
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