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MANEA anticorps (Middle Region)

L’anticorps Lapin Polyclonal anti-MANEA a été validé pour WB. Il convient pour détecter MANEA dans des échantillons de Humain, Souris, Rat, Chien, Cheval, Poisson zèbre (Danio rerio), Porc et Lapin.
N° du produit ABIN2783932

Aperçu rapide pour MANEA anticorps (Middle Region) (ABIN2783932)

Antigène

Voir toutes MANEA Anticorps
MANEA (Mannosidase, Endo-alpha (MANEA))

Reactivité

Humain, Souris, Rat, Chien, Cheval, Poisson zèbre (Danio rerio), Porc, Lapin

Hôte

  • 5
Lapin

Clonalité

  • 5
Polyclonal

Conjugué

  • 5
Cet anticorp MANEA est non-conjugé

Application

  • 5
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 1
    • 1
    • 1
    Middle Region

    Séquence

    KVTFHIEPYS NRDDQNMYKN VKYIIDKYGN HPAFYRYKTK TGNALPMFYV

    Homologie

    Dog: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 92%, Rat: 100%, Zebrafish: 77%

    Attributs du produit

    This is a rabbit polyclonal antibody against MANEA. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the middle region of human MANEA
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 462 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    MANEA (Mannosidase, Endo-alpha (MANEA))

    Autre désignation

    MANEA

    Sujet

    N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans.
    Alias Symbols: DKFZp686D20120, FLJ12838, hEndo, ENDO
    Protein Interaction Partner: UBC, DNM2, PRD, AMPH,
    Protein Size: 462

    Poids moléculaire

    54 kDa

    ID gène

    79694

    NCBI Accession

    NM_024641, NP_078917

    UniProt

    Q5SRI9
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