MANEA anticorps (Middle Region)
Aperçu rapide pour MANEA anticorps (Middle Region) (ABIN2783932)
Antigène
Voir toutes MANEA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- KVTFHIEPYS NRDDQNMYKN VKYIIDKYGN HPAFYRYKTK TGNALPMFYV
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Homologie
- Dog: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 92%, Rat: 100%, Zebrafish: 77%
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Attributs du produit
- This is a rabbit polyclonal antibody against MANEA. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human MANEA
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 462 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MANEA (Mannosidase, Endo-alpha (MANEA))
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Autre désignation
- MANEA
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Sujet
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N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans.
Alias Symbols: DKFZp686D20120, FLJ12838, hEndo, ENDO
Protein Interaction Partner: UBC, DNM2, PRD, AMPH,
Protein Size: 462 -
Poids moléculaire
- 54 kDa
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ID gène
- 79694
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NCBI Accession
- NM_024641, NP_078917
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UniProt
- Q5SRI9
Antigène
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