MANEA anticorps (Middle Region)

N° du produit ABIN2783932

L’anticorps anti-MANEA Polyclonal Lapin est utilisé pour la détection de MANEA dans des échantillons de Humain, Souris, Rat, Chien, Cheval, Poisson zèbre (Danio rerio), Porc et Lapin. Il a été validé pour WB.

Aperçu rapide pour MANEA anticorps (Middle Region) (ABIN2783932)

Antigène: MANEA (Mannosidase, Endo-alpha (MANEA))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Poisson zèbre (Danio rerio), Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MANEA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MANEA anticorps

Épitope: Middle Region

Fonction: MANEA Antibody - middle region

Séquence: KVTFHIEPYS NRDDQNMYKN VKYIIDKYGN HPAFYRYKTK TGNALPMFYV

Homologie: Dog: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 92%, Rat: 100%, Zebrafish: 77%

Attributs du produit: This is a rabbit polyclonal antibody against MANEA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MANEA

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49845-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur MANEA

Antigène: MANEA (Mannosidase, Endo-alpha (MANEA))

Autre désignation: MANEA

Sujet:

Background Information: N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans.

Gene Name: Mannosidase, endo-alpha

Alternative Symbols: ENDO, hEndo

Protein Name: Glycoprotein endo-alpha-1,2-mannosidase

Poids moléculaire: 54kDa

ID gène: 79694

NCBI Accession: NP_078917

UniProt: Q5SRI9