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ANTXR1 anticorps (Middle Region)

ANTXR1 Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2784026
  • Antigène Voir toutes ANTXR1 Anticorps
    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
    Épitope
    • 15
    • 9
    • 8
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 75
    • 39
    • 21
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval
    Hôte
    • 69
    • 3
    • 3
    Lapin
    Clonalité
    • 72
    • 3
    Polyclonal
    Conjugué
    • 34
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ANTXR1 est non-conjugé
    Application
    • 47
    • 30
    • 15
    • 13
    • 13
    • 11
    • 9
    • 5
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB)
    Séquence
    VRWGEKGSTE EGAKLEKAKN ARVKMPEQEY EFPEPRNLNN NMRRPSSPRK
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against ANTXR1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human ANTXR1
    Top Product
    Discover our top product ANTXR1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 564 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
    Autre désignation
    ANTXR1 (ANTXR1 Produits)
    Synonymes
    anticorps ANTXR1, anticorps ATR, anticorps TEM8, anticorps 2310008J16Rik, anticorps 2810405N18Rik, anticorps Antrx1, anticorps Tem8, anticorps anthrax toxin receptor 1, anticorps ANTXR1, anticorps Antxr1
    Sujet
    ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. ANTXR1 has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.The protein encoded by this gene is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants have been described.
    Alias Symbols: ATR, FLJ10601, FLJ11298, FLJ21776, TEM8
    Protein Interaction Partner: UBC, ELAVL1, Mad2l1, HDAC2, LRP6, BCL2L1,
    Protein Size: 564
    Poids moléculaire
    60 kDa
    ID gène
    84168
    NCBI Accession
    NM_032208, NP_115584
    UniProt
    Q9H6X2
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