BSCL2 anticorps (C-Term)
Aperçu rapide pour BSCL2 anticorps (C-Term) (ABIN2784048)
Antigène
Voir toutes BSCL2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- QEESTPQSDV TEDGESPEDP SGTEGQLSEE EKPDQQPLSG EEELEPEAS
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Homologie
- Cow: 86%, Dog: 86%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against BSCL2. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human BSCL2
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 462 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))
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Autre désignation
- BSCL2
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Sujet
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This gene encodes protein seipin, which is located in the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: GNG3LG, HMN5, MGC4694, SPG17
Protein Interaction Partner: SMLR1, SMIM3, PLEKHF2, TMEM19, NSG1, SUMO2, SUMO3, Hoxa1, UBC, CANX, USE1,
Protein Size: 462 -
Poids moléculaire
- 51 kDa
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ID gène
- 26580
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NCBI Accession
- NM_001122955, NP_001116427
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UniProt
- Q96G97
Antigène
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