FCRLA anticorps (C-Term)

N° du produit ABIN2784054

L’anticorps anti-FCRLA Polyclonal Lapin est utilisé pour la détection de FCRLA dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour FCRLA anticorps (C-Term) (ABIN2784054)

Antigène: FCRLA (Fc Receptor-Like A (FCRLA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FCRLA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FCRLA anticorps

Épitope: C-Term

Fonction: FCRLA Antibody - C-terminal region

Séquence: MPDPHLYHQM GLLLKHMQDV RVLLGHLLME LRELSGHRKP GTTKATAE

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against FCRLA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human FCRLA

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50111-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur FCRLA

Antigène: FCRLA (Fc Receptor-Like A (FCRLA))

Autre désignation: FCRLA

Sujet:

Background Information: Receptors for the Fc fragment of IgG, or FCGRs, are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. FCRLA may be implicated in B-cell differentiation and lymphomagenesis.Receptors for the Fc fragment of IgG, or FCGRs (see MIM 146790), are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. All FCGR genes map to human chromosome 1. Additional genes in this region, including FREB, encode FCGR homologs that are selectively expressed in B cells and may be implicated in B-cell development and lymphomagenesis.[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-742 BM471887.1 3-744 743-1338 BC006521.2 558-1153 1339-1684 BX112608.1 318-663 1685-2357 BX649184.1 2243-2915

Gene Name: Fc receptor-like A

Alternative Symbols: FCRL, FCRX, FREB, FCRL1, FCRLX, FCRLb, FCRLd, FCRLe, FCRLM1, FCRLc1, FCRLc2

Protein Name: Fc receptor-like A

Poids moléculaire: 41kDa

ID gène: 84824

NCBI Accession: NP_116127

UniProt: Q7L513