RFT1 anticorps (N-Term)

N° du produit ABIN2784093

Cet anticorps Lapin Polyclonal détecte spécifiquement RFT1 dans WB. Il présente une réactivité envers Humain, Chien, Souris, Boeuf (Vache), Cobaye, Cheval, Lapin et Rat.

Aperçu rapide pour RFT1 anticorps (N-Term) (ABIN2784093)

Antigène: RFT1 (RFT1 Homolog (RFT1))

Reactivité: Humain, Chien, Souris, Boeuf (Vache), Cobaye, Cheval, Lapin, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RFT1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RFT1 anticorps

Épitope: N-Term

Séquence: GTQRDWSQTL NLLWLTVPLG VFWSLFLGWI WLQLLEVPDP NVVPHYATGV

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 85%, Rabbit: 92%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against RFT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RFT1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 541 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RFT1

Antigène: RFT1 (RFT1 Homolog (RFT1))

Autre désignation: RFT1

Sujet: N-glycosylation of proteins follows a highly conserved pathway that begins with the synthesis of a!!Man(5)GlcNAc(2)-dolichylpyrophosphate (PP-Dol) intermediate on the cytoplasmic side of the endoplasmic reticulum (ER) membrane followed by the translocation of Man(5)GlcNAc (2)-PP-Dol to the luminal side of the ER membrane. RFT1 is the flippase enzyme that catalyzes this translocation.N-glycosylation of proteins follows a highly conserved pathway that begins with the synthesis of a Man(5)GlcNAc(2)-dolichylpyrophosphate (PP-Dol) intermediate on the cytoplasmic side of the endoplasmic reticulum (ER) membrane followed by the translocation of Man(5)GlcNAc (2)-PP-Dol to the luminal side of the ER membrane. RFT1 is the flippase enzyme that catalyzes this translocation (Helenius et al., 2002 [PubMed 11807558]).[supplied by OMIM].
Alias Symbols: CDG1N
Protein Interaction Partner: PSMA3, UBC, NEDD4,
Protein Size: 541

Poids moléculaire: 60 kDa

ID gène: 91869

NCBI Accession: NM_052859, NP_443091

UniProt: Q96AA3