Ataxin 3 anticorps (N-Term)

N° du produit ABIN2784210

L’anticorps Lapin Polyclonal anti-Ataxin 3 a été validé pour WB. Il convient pour détecter Ataxin 3 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Mouton, Cheval, Lapin, Cobaye, Chien et Poisson zèbre (Danio rerio).

Aperçu rapide pour Ataxin 3 anticorps (N-Term) (ABIN2784210)

Antigène: Ataxin 3 (ATXN3)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Mouton, Cheval, Lapin, Cobaye, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ataxin 3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Ataxin 3 anticorps

Épitope: N-Term

Séquence: SIAHQLDEEE RMRMAEGGVT SEDYRTFLQQ PSGNMDDSGF FSIQVISNAL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against ATXN3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ATXN3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 361 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Ataxin 3

Antigène: Ataxin 3 (ATXN3)

Autre désignation: ATXN3

Sujet: Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: AT3, ATX3, JOS, MJD, MJD1, SCA3
Protein Interaction Partner: UBC, NEDD8, ATXN3, TRIM63, SQSTM1, VCP, ITCH, PARK2, MGRN1, TUBB, HDAC6, TUBA1A, ELC1, ELA1, SYVN1, BAG3, BCL2L1, STUB1, SUMO1, APP, RFFL, TRIM55, SPRTN, PJA1, TRIM54, USP21, UBE2L3, ARHGDIA, ASIC1, RAD23B, RAD23A, ARHGAP19, C16orf70, TEX11, PICK1, GSK3B,
Protein Size: 361

Poids moléculaire: 41 kDa

ID gène: 4287

NCBI Accession: NM_004993, NP_004984

UniProt: P54252