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ING1 anticorps (C-Term)

L’anticorps anti-ING1 Polyclonal Lapin est utilisé pour la détection de ING1 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Poisson zèbre (Danio rerio), Cheval et Lapin. Il a été validé pour WB.
N° du produit ABIN2784213
470,22 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 6 à 9 jours ouvrables

Aperçu rapide pour ING1 anticorps (C-Term) (ABIN2784213)

Antigène

Voir toutes ING1 Anticorps
ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Reactivité

  • 75
  • 18
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Poisson zèbre (Danio rerio), Cheval, Lapin

Hôte

  • 69
  • 6
  • 2
Lapin

Clonalité

  • 68
  • 9
Polyclonal

Conjugué

  • 33
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp ING1 est non-conjugé

Application

  • 51
  • 23
  • 13
  • 13
  • 13
  • 8
  • 7
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB)
  • Épitope

    • 15
    • 12
    • 10
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Fonction

    ING1 Antibody - C-terminal region

    Séquence

    EKKAKTSKKK KRSKAKAERE ASPADLPIDP NEPTYCLCNQ VSYGEMIGCD

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

    Attributs du produit

    This is a rabbit polyclonal antibody against ING1. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Protein A purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the C terminal region of human ING1
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Commentaires

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8103042

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1.0 mg/mL

    Buffer

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    prevent freeze-thaw cycles

    Stock

    4 °C,-20 °C

    Stockage commentaire

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    ING1 (Inhibitor of Growth Family, Member 1 (ING1))

    Autre désignation

    ING1

    Sujet

    Background Information: ING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. The protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of ING1 gene have been detected in various cancers.This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

    Gene Name: Inhibitor of growth family, member 1

    Alternative Symbols: p33, p47, p33ING1, p24ING1c, p33ING1b, p47ING1a

    Protein Name: Inhibitor of growth protein 1

    Poids moléculaire

    32kDa

    ID gène

    3621

    NCBI Accession

    NP_937862

    UniProt

    Q5T9H0

    Pathways

    Protein targeting to Nucleus, Autophagy
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