TRAPPC2 anticorps (Middle Region)
Aperçu rapide pour TRAPPC2 anticorps (Middle Region) (ABIN2784240)
Antigène
Voir toutes TRAPPC2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- RQEDGIKNFF TDVYDLYIKF SMNPFYEPNS PIRSSAFDRK VQFLGKKHLL
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against TRAPPC2. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human TRAPPC2
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 140 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TRAPPC2 (Trafficking Protein Particle Complex 2 (TRAPPC2))
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Autre désignation
- TRAPPC2
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Sujet
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TRAPPC2 prevents MBP1-mediated transcriptional repression and antagonizes MBP1-mediated cell death. TRAPPC2 may play a role in vesicular transport from endoplasmic reticulum to Golgi.The protein encoded by this gene is thought to be part of a large multisubunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind MBP1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseuodogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been found for this gene.
Alias Symbols: MIP-2A, SEDL, SEDT, TRS20, ZNF547L, hYP38334, MIP2A, TRAPPC2P1
Protein Interaction Partner: TRAPPC3L, TRAPPC5, TRAPPC6B, TRAPPC9, TRAPPC6A, TRAPPC11, TRAPPC4, TRAPPC12, TRAPPC3, TRAPPC8, TRAPPC10, ELAVL1, UBC, JOSD2, CLIC1, CLIC2, ENO1,
Protein Size: 140 -
Poids moléculaire
- 16 kDa
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ID gène
- 6399
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NCBI Accession
- NM_014563, NP_055378
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UniProt
- O14582
Antigène
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